Bakshi Finance

Amgen Inc. (AMGN)

Healthcare · Thousand Oaks, California · NASDAQ

AMGN
Value | Tactical NASDAQ Research Depth · Standard

Company Description

Amgen Inc. (AMGN) is among the 10 largest biotech companies globally by revenue [source: 10-K FY2025 Item 1] (founded 1980), with a portfolio of 15+ commercial drugs across oncology, cardiovascular, inflammation, and bone health. In FY2025 the company reported revenue of $34.9B (+4.4% Y/Y) across a diversified portfolio: Osteoporosis franchise (Prolia+Evenity) $7.2B (20.6%, +10% Y/Y), Repatha $2.8B (8.0%, **+30% — growth leader**), Enbrel $3.5B (10.0%, -12% — patent expiring 2029), Oncology (Blincyto+Kyprolis+Vectibix) $5.8B (16.6%, +14%), and TEPEZZA/Horizon-acquired pipeline $2.2B (+6%). The Horizon Therapeutics acquisition ($27.8B, 2023) added $55B in debt, weighing on the balance sheet with Net Debt of $47B. MariTide (obesity — Phase 3 readout per company guidance 2026) is the central item under watch positioning the company toward the GLP-1 market of $150B+. Op Margin 26.9%, FCF $10.3B, Dividend Yield 3.5% (21 consecutive years of growth). CEO+Chairman Bob Bradway (since 2012) — the dual role represents a governance flag.
Sector · Sub-sectorHealthcare · Biotechnology
[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
HeadquartersThousand Oaks, California
[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
Founded1980
[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
CEORobert A. Bradway
[AMGN DEF 14A filed 2026-04-07 · accession 0001193125-26-145588]
ChairmanRobert A. Bradway
[AMGN DEF 14A filed 2026-04-07 · accession 0001193125-26-145588]
Employees~28,000
[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
Market Cap$145.3B
[snapshot 2026-04-17]
Revenue FY2025$36.8B
[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
Net Income$7.7B
[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
Shares Outstanding537M
[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
Market Cap
$145.3B
537M | P/E 19.01
[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010] · [yfinance snapshot 2026-04-17]
Revenue FY2025
$36.8B
+10.0% Y/Y
[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
Net Income
$7.7B
EPS $14.23 | +88.5% Y/Y
[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
Gross Margin
61.6%
Op Margin 26.9%
[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
FCF
$10.3B
FCF Yield (snapshot) 7.09%
[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010] · snapshot 2026-04-17
Net Debt
$47.0B Net Debt
Debt $58B | Cash $12B
[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
Closing Price
$270.50
As of 2026-04-17
[yfinance snapshot 2026-04-17]
1

Financial Performance — 5 Years

Revenue ($M)
Last 5 fiscal years
Operating Income & Margin
Multi-year trend
EBITDA & Free Cash Flow
5-year trend
Revenue Mix
Latest fiscal year
Profitability Margins — 5 Years
Gross / Operating / Net Margin %
Capital Structure
Cash, Debt, Net Debt | 5 years
2

Financial Statements

ItemFY-4FY-3FY-2FY-1FY (latest)Source
Revenue$26.0B$26.3B$28.2B$33.4B$36.8B[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
Gross Profit$19.2B$19.1B$17.9B$20.4B$21.5B[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
Operating Income$9.1B$9.6B$7.9B$7.3B$9.1B[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
Operating Margin %35.2%36.3%29.2%25.6%26.9%[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
EBITDA$12.2B$12.7B$12.5B$13.4B$14.5B[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
Net Income$5.9B$6.6B$6.7B$4.1B$7.7B[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
EPS ($)$10.28$12.11$12.49$7.56$14.23[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
FCF$8.4B$8.7B$7.5B$9.3B$10.3B[AMGN 10-K filed 2026-02-13 · accession 0000318154-26-000010]
3

Economic Moat

Sources of Moat
[Fact — 10-K FY2025] 15+ blockbuster drugs, 5+ with >$1B revenue★★★★☆
Biologics manufacturing scale (rare capability)★★★★☆
21 consecutive years dividend growth (Dividend Aristocrat)★★★★☆
MariTide pipeline (obesity GLP-1-like) Phase 3★★★★☆
Oncology franchise long tails (Blincyto, Kyprolis)★★★★☆
4

Multiples & Valuation

MultipleCompanyOwn 5Y AverageDelta vs 5Y Avg
P/E (TTM) [yfinance snapshot · 5Y computed 2026-04-18]19.0x25.6x (5Y)-25.6%
P/E (Fwd) [yfinance forward consensus]16.1xN/AN/A
EV/EBITDA [yfinance snapshot · 5Y computed 2026-04-18]14.1x13.8x (5Y)+2.2%
P/S [yfinance snapshot · 5Y computed 2026-04-18]4.2x5.0x (5Y)-16.0%
P/B [yfinance snapshot · 5Y computed 2026-04-18]22.3x26.8x (5Y)-16.8%
Div Yield [yfinance snapshot · 5Y computed 2026-04-18]3.50%3.08% (5Y)+0.42pp
FCF Yield (snapshot) [computed · 2026-04-18]7.09%5.76% (5Y)+23.1%
The 5Y statistical averages are computed from yfinance annual data (annual income_stmt × balance_sheet × cash_flow + price snapshots at FY-end). Source: lib/compute_5y_multiples.py · Refresh: 2026-04-18
5

How to Think About This Company

The full How to Think About This Company analysis for AMGN — covering an examination of the essence, the central variables, potential analytical pitfalls, and what distinguishes professional thinking from noise — is available within the Family Office content.

The difference between surface-level analysis and professional thinking often lies in the variables that are not immediately visible.

7

Risks & Items Under Watch

Key Risks
[WARN][Fact — 10-K FY2025] Enbrel patent expires 2029 — $3.5B revenue at risk
[WARN][Fact — 10-K FY2025] Net Debt $47B (Horizon acquisition) — Debt/EBITDA 3.2x
[WARN]MariTide Phase 3 readout — binary event 2026
[WARN]IRA drug price negotiation — Prolia, Repatha exposed
[WARN][Fact — 10-K FY2025] TEPEZZA (Horizon) growth slower than acquisition thesis
[WARN][Fact — DEF 14A] Bob Bradway CEO+Chairman dual role — governance concern
Items Under Watch
[Strength] [Fact — 10-K FY2025] 15+ blockbuster drugs, 5+ with >$1B revenue
[Strength] [Fact] Biologics manufacturing scale (rare capability)
[Strength] [Assessment] 21 consecutive years dividend growth (Dividend Aristocrat)
[Strength] [Fact] MariTide pipeline (obesity GLP-1-like) Phase 3
[Strength] [Assessment] Oncology franchise long tails (Blincyto, Kyprolis)
[Bull Scenario] Conditional: if MariTide Phase 3 succeeds, Horizon synergies materialize, and the biosimilar portfolio scales — operating leverage may improve materially.
8

Scenario Framework

The framework below describes which conditions would need to hold in each scenario — not a price forecast.

Scenarios are descriptive, not predictive. They outline possible conditions, not expected outcomes. These scenarios contain no probability assessment, no preferred direction, and no expectation as to which one will materialize.

Bull Case
[Scenario — Bakshi Finance internal assumption] Conditional: if MariTide Phase 3 succeeds, Horizon synergies materialize, and the biosimilar portfolio scales — earnings power could improve materially. [source: Bakshi scenario model V2.7]
Base Case
[Scenario — Bakshi Finance internal assumption] Conditional: if Enbrel decline is offset by Repatha/Oncology growth and MariTide is launched FY27 — the existing earnings profile may persist. [source: Bakshi scenario model V2.7]
Bear Case
[Scenario — Bakshi Finance internal assumption] Conditional: if MariTide Phase 3 fails, Enbrel erodes faster, and IRA cuts Prolia pricing — earnings power may compress. [source: Bakshi scenario model V2.7]
The framework describes conditions, not forecasts. There is no preferred direction, probability assessment, or price target in this framework.
10

Analytical Lens — The Questions We Ask

In professional company analysis, the question is not "is this good", but rather "what angles must we examine in order not to miss the essentials". Every analysis at Bakshi Finance passes through six angles. The text below is not an assessment — it is the mapping of the questions this analysis is intended to answer.

The analysis is based on an internal multi-factor analytical framework used in professional portfolio management. The framework maps the questions; the answers appear woven through the analysis above.

What the lens is not: there is no rating here, no score, no comparison between this company and any other, and no preference. The same six questions are asked of every company on the site — what differs is the answers, not the tool.

This framework is intended to structure analysis, not to produce an investment conclusion.

1.
Growth
How does the company grow? Does growth come from volume, price, or mix? Is it stable across cycles?
2.
Profitability
How do margins behave over time? How much of accounting profit converts to actual free cash flow?
3.
Leverage
What is the capital structure? With what flexibility would the company handle a downturn or higher financing costs?
4.
Competitive Position
What protects its revenue from erosion? How long is that protection expected to hold?
5.
Management Quality
How does management allocate capital? What is its track record on strategic decisions?
6.
Business Complexity / Risk
Where would simplistic analysis go wrong? What is exposed to regulation, cyclicality, or technological change?

Key Observations

This summary is not a recommendation. It is a factual list of what the analysis identified. The decision — belongs to the client.

Disclosure — Family Office Format

Bakshi Finance operates as a Family Office for qualified investors only. Mr. Yaron Bakshi held a licensed investment advisory license from 2008 to 2023. As of the publication date of this document, the firm does not hold a license for investment advice, investment marketing, or portfolio management.

This document is intended for research and professional study purposes only. Nothing herein constitutes a recommendation to buy, sell, hold, or take any other action in any security. Nothing herein substitutes for advice that takes into account each individual's data and needs. Every decision — rests solely with the investor.

Past performance is no indication of future performance. Scenarios are descriptive, not predictive, and do not represent price targets or expected outcomes.