Bakshi Finance

Gilead Sciences, Inc.

Healthcare · Foster City, California · NASDAQ

GILD
Value | Core/Tactical NASDAQ Research Depth · Standard

Company Description

Gilead Sciences is a U.S. biotechnology company focused on the development of therapies for HIV, oncology, and liver diseases. Its portfolio includes Biktarvy — the world's leading HIV treatment with 80%+ U.S. market share — as well as Yescarta/Tecartus from Kite (acquired in 2017) in the CAR-T space for treating various forms of lymphoma [source: GILD 10-K FY2025 Item 1]. Gilead's moat is built on a fortified HIV franchise: Biktarvy has cultivated physician and patient loyalty over a decade, and its primary patent does not expire until 2033 — providing the company with another decade of high cash flows. Alongside this defense, Kite CAR-T (Yescarta) maintains the #1 position in CAR-T lymphoma even as competition from Bristol-Myers Squibb and Novartis has entered the market [source: GILD 10-K FY2025 Item 1 Competition]. Revenue model: branded drug sales + royalties + new growth pipeline. Operating margin of 35%+ and gross margin of 76% — biotech premium levels. The near-term item under watch is Lenacapavir — a long-acting (six-month) HIV prevention therapy that delivered positive Phase 3 results in 2024 and begins commercialization in 2026; according to company guidance, peak sales potential is $3-5B. Risk factors: under the IRA (Inflation Reduction Act), Biktarvy may be subject to Medicare price negotiation, and Veklury (a COVID antiviral) is showing a sustained post-pandemic revenue decline [source: GILD 10-K FY2025 Item 1A].
Sector · Sub-SectorHealthcare · Drug Manufacturers - General
[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
HeadquartersFoster City, California
[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
Year Founded1987
[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
CEOMr. Daniel P. O'Day
[GILD DEF 14A filed 2026-03-20 · accession 0001308179-26-000106]
ChairmanN/A
[GILD DEF 14A filed 2026-03-20 · accession 0001308179-26-000106]
Employees~17,000
[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
Market Cap$170.8B
[snapshot 2026-04-17]
Revenue FY2025$29.4B
[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
Net Income$8.5B
[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
Shares Outstanding1,241M
[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
Market Cap
$170.8B
1,241M | P/E 20.27
[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006] · [yfinance snapshot 2026-04-17]
Revenue FY2025
$29.4B
+2.4% Y/Y
[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
Net Income
$8.5B
EPS $6.78 | +1672.9% Y/Y
[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
Gross Margin
78.8%
Op Margin 39.7%
[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
FCF
$9.5B
FCF Yield (snapshot) 5.54%
[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006] · snapshot 2026-04-17
Net Debt
$15.3B Net Debt
Debt $25B | Cash $10B
[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
Closing Price
$137.64
As of 2026-04-17
[yfinance snapshot 2026-04-17]
1

Financial Performance — 5 Years

Revenue ($M)
Last 5 fiscal years
Operating Income & Margin
Multi-year trend
EBITDA & Free Cash Flow
5-year trend
Revenue Breakdown
Latest fiscal year
Profitability Margins — 5 Years
Gross / Operating / Net Margin %
Capital Structure
Cash, Debt, Net Debt | 5 years
2

Financial Statements

ItemFY-4FY-3FY-2FY-1FY (latest)Source
Revenue$27.3B$27.1B$28.8B$29.4B[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
Gross Profit$21.6B$20.6B$22.5B$23.2B[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
Operating Income$11.0B$8.8B$10.6B$11.7B[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
Operating Margin %40.2%32.6%36.9%39.7%[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
EBITDA$13.2B$11.9B$13.6B$14.8B[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
Net Income$4.6B$5.7B$480.0M$8.5B[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
EPS ($)$3.64$4.50$0.38$6.78[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
FCF$8.3B$7.4B$10.3B$9.5B[GILD 10-K filed 2026-02-24 · accession 0000882095-26-000006]
3

Economic Moat

Moat Sources
[source: GILD 10-K FY2025] HIV franchise — 80% market share in US (Biktarvy)★★★★☆
[source: GILD 10-K FY2025] Kite CAR-T leadership (Yescarta lymphoma)★★★★☆
[source: GILD 10-K FY2025] R&D pipeline 60+ clinical programs★★★★☆
[source: GILD Q4 FY2025 earnings] Lenacapavir PrEP launch projected by company guidance for 2026★★★★☆
[source: GILD 10-K FY2025] Dividend ~4% yield, growth streak★★★★☆
4

Multiples & Valuation

MultipleCompany5Y Self AvgDelta vs 5Y Avg
P/E (TTM) [yfinance snapshot · 5Y computed 2026-04-18]20.3x75.7x (4Y)-73.2%
P/E (Fwd) [yfinance forward consensus]14.3xN/AN/A
EV/EBITDA [yfinance snapshot · 5Y computed 2026-04-18]12.8x10.1x (4Y)+26.8%
P/S [yfinance snapshot · 5Y computed 2026-04-18]5.8x4.2x (4Y)+37.8%
P/B [yfinance snapshot · 5Y computed 2026-04-18]7.5x5.5x (4Y)+36.0%
Div Yield [yfinance snapshot · 5Y computed 2026-04-18]2.38%3.32% (4Y)-0.94pp
FCF Yield (snapshot) [computed · 2026-04-18]5.54%7.57% (4Y)-26.8%
5Y statistical averages computed from yfinance annual data (annual income_stmt × balance_sheet × cash_flow + price snapshots at FY-end). Source: lib/compute_5y_multiples.py · Refresh: 2026-04-18
5

How to Think About This Company

A full How to Think About This Company analysis for GILD — covering the essence of the business, the key variables, potential analytical pitfalls, and what distinguishes professional thinking from noise — is available within the Family Office content offering.

The difference between surface-level analysis and professional thinking often lies in the variables that are not immediately visible.

7

Risks & Items Under Watch

Key Risks
[WARN][source: GILD 10-K FY2025 Item 1A] Biktarvy patent expiry 2033 (long-tail)
[WARN][source: GILD 10-K FY2025] Oncology competition (BMS, Novartis CAR-T)
[WARN][source: GILD 10-K FY2025] IRA Medicare Negotiation — HIV exposed
[WARN][source: GILD 10-K FY2025] Veklury (COVID) revenue declining
[WARN][source: GILD 10-K FY2025] M&A integration (Immunomedics, CymaBay)
[WARN][source: GILD 10-K FY2025 Item 1A] Pipeline approval timing
Items Under Watch
[Strength] HIV franchise — 80% market share in US (Biktarvy)
[Strength] Kite CAR-T leadership (Yescarta lymphoma)
[Strength] R&D pipeline 60+ clinical programs
[Strength] Lenacapavir PrEP launch projected by company guidance for 2026
[Strength] Dividend ~4% yield, growth streak
[Bull Conditions] Lenacapavir scales + Oncology wins + CymaBay PSC success — conditions that would need to materialize for an upside scenario
8

Scenario Framework

The framework below describes what conditions would need to hold in each scenario — not a price forecast.

Scenarios are descriptive, not predictive. They outline possible conditions, not expected outcomes. No probability is assigned, no scenario is preferred, and no view is offered on which one will materialize.

Bull Case
[scenario — internal Bakshi Finance assumption] Upside conditions [source: Bakshi scenario model V2.7]
Base Case
[scenario — internal Bakshi Finance assumption] Mid-range conditions [source: Bakshi scenario model V2.7]
Bear Case
[scenario — internal Bakshi Finance assumption] Downside conditions [source: Bakshi scenario model V2.7]
The framework describes conditions, not forecasts. There is no preferred direction, no probability assigned, and no price targets within this framework.
10

Analytical Lens — The Questions We Ask

In a professional company analysis, the question is not "is this good," but rather "through which lenses must the company be examined so that nothing essential is missed." Every analysis at Bakshi Finance passes through six lenses. The text below is not an evaluation — it is a mapping of the questions this analysis is designed to answer.

The analysis is based on an internal multi-factor analytical framework used in professional portfolio management. The framework maps the questions; the answers appear woven through the analysis above.

What the lens is not: there is no rating here, no score, no comparison between this company and another, and no preference. The same six questions are asked of every company on the site — the difference lies in the answers, not the tool.

This framework is intended to structure analysis, not to produce an investment conclusion.

Growth
How is the company growing? Is the growth driven by volume, by price, or by mix? Is it stable across cycles?
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Profitability
How do margins behave over time? How much of accounting profit converts into actual free cash flow?
Leverage
What is the capital structure? With what flexibility could the company face a downcycle or higher financing costs?
Competitive Position
What protects its revenues from erosion? How long is that protection likely to hold?
Management Quality
How does management allocate capital? What is its track record on strategic decisions?
Business Complexity / Risk
Where would a simplistic analysis go wrong? What is exposed to regulation, cyclicality, or technological change?

Key Observations

This summary is not a recommendation. It is a factual list of what the analysis identified. The decision — rests with the client.

Disclosure — Family Office Format

Bakshi Finance operates as a Family Office serving qualified investors only. Mr. Yaron Bakshi held a licensed investment advisory license between 2008 and 2023. As of the publication date of this document, the firm does not hold an investment advisory license, an investment marketing license, or a portfolio management license. This document is for professional research and educational purposes only.

Nothing herein constitutes a recommendation to buy, sell, hold, or otherwise transact in any security. Nothing herein is a substitute for advice tailored to the data and needs of any particular person. Any decision is made at the sole responsibility of the investor.

Past performance is not indicative of future results.